Make Room for Worry & Provision

Jesus addresses his followers and instructs them not to worry. What are we supposed to do with this in an era of rising anxiety and mental health diagnoses? There are many things we can be worried about, and Jesus tells us we do not have to worry about our basic needs like food and clothing. What are we supposed to do with statements like this? What can we trust God to provide for us? How do we remain diligent in a God-honoring way, but not give in to worry? How can we engage God in our worries?